YEARS
An inflammatory state defines a high-risk T-lineage acute lymphoblastic leukemia subgroup

Gower M, Li X, Aguilar-Navarro AG, Lin B, Fernandez M, Edun G, Nader M, Rondeau V, Arruda A, Tierens A, Eames Seffernick A, Pölönen P, Durocher J, Wagenblast E, Yang L, Lee HS, Mullighan CG, Teachey D, Rashkovan M, Tremblay CS, Herranz D, Itkin T, Loghavi S, Dick JE, Schwartz G, Perusini MA, Sibai H, Hitzler J, Gruber TA, Minden M, Jones CL, Dolgalev I, Jahangiri S, Tikhonova AN. An inflammatory state defines a high-risk T-lineage acute lymphoblastic leukemia subgroup

Science Translational Medicine Vol. 17, No. 779

Under the surface: scratching the ALL niche

Mark Gower and Anastasia Tikhonova

Haematologica

Treatment response in AML—clues in the biopsy core

Alicia G. Aguilar Navarro and Anastasia N. Tikhonova

British Journal of Hematology

Avoiding fratricide: a T-ALL order

Mark Gower, Anastasia N. Tikhonova

Blood (2022) 140 (1): 3–4.

Stem cells pack some chillis for the road

Anastasia N. Tikhonova & Iannis Aifantis

Nature 589, 520-521 (2021)

There won’T be blood

Mark Gower, Gena Foster & Anastasia N. Tikhonova

Nat Immunol (2021). https://doi.org/10.1038/s41590-021-00893-6

Connecting the Dots: Resolving the Bone Marrow Niche Heterogeneity

Igor Dolgalev and Anastasia N. Tikhonova

Front. Cell Dev. Biol., 12 March 2021

Cell-by-Cell Deconstruction of Stem Cell Niches

Tikhonova A.N. #, A. Lasry, R. Austin, and I. Aifantis#

Cell Stem Cell 27 (1): 19-34.

The bone marrow microenvironment at single-cell resolution

Tikhonova, A. N.*#, I. Dolgalev*, H. Hu, K. K. Sivaraj, E. Hoxha, A. Cuesta-Dominguez, S. Pinho, I. Akhmetzyanova, J. Gao, M. Witkowski, M. Guillamot, M. C. Gutkin, Y. Zhang, C. Marier, C. Diefenbach, S. Kousteni, A. Heguy, H. Zhong, D. R. Fooksman, J. M. Butler, A. Economides, P. S. Frenette, R. H. Adams, R. Satija, A. Tsirigos# and I. Aifantis#

Nature 569(7755): 222-228

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance

Pitt, L. A.*, A. N. Tikhonova*, H. Hu, T. Trimarchi, B. King, Y. Gong, M. Sanchez-Martin, A. Tsirigos, D. R. Littman, A. A. Ferrando, S. J. Morrison, D. R. Fooksman, I. Aifantis and S. R. Schwab

Cancer Cell 27(6): 755-768

Lck availability during thymic selection determines the recognition specificity of the T cell repertoire.

Van Laethem, F., A. N. Tikhonova, L. A. Pobezinsky, X. Tai, M. Y. Kimura, C. Le Saout, T. I. Guinter, A. Adams, S. O. Sharrow, G. Bernhardt, L. Feigenbaum and A. Singer

Cell 154(6): 1326-1341

An inflammatory state defines a high-risk T-lineage acute lymphoblastic leukemia subgroup

Gower M, Li X, Aguilar-Navarro AG, Lin B, Fernandez M, Edun G, Nader M, Rondeau V, Arruda A, Tierens A, Eames Seffernick A, Pölönen P, Durocher J, Wagenblast E, Yang L, Lee HS, Mullighan CG, Teachey D, Rashkovan M, Tremblay CS, Herranz D, Itkin T, Loghavi S, Dick JE, Schwartz G, Perusini MA, Sibai H, Hitzler J, Gruber TA, Minden M, Jones CL, Dolgalev I, Jahangiri S, Tikhonova AN. An inflammatory state defines a high-risk T-lineage acute lymphoblastic leukemia subgroup

Science Translational Medicine Vol. 17, No. 779

Under the surface: scratching the ALL niche

Mark Gower and Anastasia Tikhonova

Haematologica

Treatment response in AML—clues in the biopsy core

Alicia G. Aguilar Navarro and Anastasia N. Tikhonova

British Journal of Hematology

Avoiding fratricide: a T-ALL order

Mark Gower, Anastasia N. Tikhonova

Blood (2022) 140 (1): 3–4.

Stem cells pack some chillis for the road

Anastasia N. Tikhonova & Iannis Aifantis

Nature 589, 520-521 (2021)

There won’T be blood

Mark Gower, Gena Foster & Anastasia N. Tikhonova

Nat Immunol (2021). https://doi.org/10.1038/s41590-021-00893-6

Connecting the Dots: Resolving the Bone Marrow Niche Heterogeneity

Igor Dolgalev and Anastasia N. Tikhonova

Front. Cell Dev. Biol., 12 March 2021

Cell-by-Cell Deconstruction of Stem Cell Niches

Tikhonova A.N. #, A. Lasry, R. Austin, and I. Aifantis#

Cell Stem Cell 27 (1): 19-34.

The bone marrow microenvironment at single-cell resolution

Tikhonova, A. N.*#, I. Dolgalev*, H. Hu, K. K. Sivaraj, E. Hoxha, A. Cuesta-Dominguez, S. Pinho, I. Akhmetzyanova, J. Gao, M. Witkowski, M. Guillamot, M. C. Gutkin, Y. Zhang, C. Marier, C. Diefenbach, S. Kousteni, A. Heguy, H. Zhong, D. R. Fooksman, J. M. Butler, A. Economides, P. S. Frenette, R. H. Adams, R. Satija, A. Tsirigos# and I. Aifantis#

Nature 569(7755): 222-228

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance

Pitt, L. A.*, A. N. Tikhonova*, H. Hu, T. Trimarchi, B. King, Y. Gong, M. Sanchez-Martin, A. Tsirigos, D. R. Littman, A. A. Ferrando, S. J. Morrison, D. R. Fooksman, I. Aifantis and S. R. Schwab

Cancer Cell 27(6): 755-768

Lck availability during thymic selection determines the recognition specificity of the T cell repertoire.

Van Laethem, F., A. N. Tikhonova, L. A. Pobezinsky, X. Tai, M. Y. Kimura, C. Le Saout, T. I. Guinter, A. Adams, S. O. Sharrow, G. Bernhardt, L. Feigenbaum and A. Singer

Cell 154(6): 1326-1341