Every process in our body is mediated by highly orchestrated cellular cross-talk. We are interested in understanding how the cellular dialog is established, maintained, and altered by stress. Our research program is bridging rigorous genomic studies of the bone marrow niche with clinical outcomes to devise rational and targeted therapies via the following three directions:
Stress-mediated Bone Marrow Niche remodeling
In and Out of the Bone
Under the surface: scratching the ALL niche
Treatment response in AML—clues in the biopsy core
Avoiding fratricide: a T-ALL order
Huge congrats to Alicia for receiving PM postdoctoral fellowship to study leukemia-mediated remodelling of the bone marrow niche!🥳 Funds are provided by the Next Generation Research Fellowship Fund.